I have a 6.2 with a Comp VVT 214/228 cam, 1 7/8th catted headers exiting through the stock 3.5" exhaust. Its a very strong combination. I'm considering putting on the AFM hardware from my 5.3 and getting one of Texas-speed's AFM/VVT cams. My main concern here drive-ability and engine noise. One of these cams would allow me to use the LS3 springs and the very mild lobes would make it sound stock again. The engine and exhaust noise are definitely a concern as I leave for work around 6 in the morning.

And I know everyone hates AFM, but I had my 5.3 staying in 4-cylinder mode for long stretches and I think the 6.2 could do even better.

I'm also considering putting a blower on top of all of this.

 

I think that would be an awesome combo personally and only made better by the blower. With those mild lobes the blower would really help get the air into the cylinders to net you an awesome driving, quiet, low maintenance setup. I'd do the blower first then the cam so you can get the tune pretty well under control so you'll just be rich when you throw the smaller cam in.