So, I'm about to do some work to my 4.8. I'll be running a EPS Cam (214/222 .595 .602 on a 113+2) and 243 heads milled .040 with .040 head gaskets. Will PTV clearance be a problem with this setup?

 

I think you will be good. But Just check it. Pump up the lifters and zero lash and add .100 turn the engine over by hand and threw the 4 stroke of the engine you are good. just make sure the lifter are pump up tight. I use a old lifter that I open it up make a piece to make it soild checking PTV.

 

Alright. Sounds good. Thanks

 

A better way is to put a checker valve spring on a cylinder and measure the clearance with a dial indicator. Its usually closest 5-15 degrees ATDC.