5.3 to 6.0
#2
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Try to stick to a 2001-2006 6.0. The early lq4s had a longer crank due to being mated to the 4l80e. They upgraded the connecting rods in 2005. Keep in mind that the 2003+ engines are Drive by wire and use an electronic throttle body. You'll have to slap the intake you have know on it.
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#8
Everything should swap over, we did the same thing on my brothers 2000 Silverado. You can drive it without a tune but you will need one eventually. Just as a heads up, our tuner told us that the stock 5.3 injectors were close to maxed out, so you may want to upgrade.